Serum immunoglobulins in juvenile rheumatoid arthritis.

Serum immunoglobulins in juvenile rheumatoid arthritis.

Juvenile rheumatoid arthritis (JRA) differs in many aspects from its adult counterpart (Edstrom, 1958); one of the differences is a low incidence of positive sero-reactions for rheumatoid factors (RF) in patients with JRA (Bywaters, Carter, and Scott, 1959; Sievers, Ahvonen, Aho, and Wager, 1963; Ansell, 1966). Although the agglutinating activity of RF was found in different classes of immunogl...

Serum antigammaglobulins in juvenile rheumatoid arthritis.

Levels of serum immunoglobulins in patients with rheumatoid arthritis.

Quantitative and qualitative modifications of the plasma proteins are of particular importance among the systemic manifestations of rheumatoid arthritis. Increase of a2and y-globulins may be found in most patients (Ropes, Perlmann, Kaufman, and Bauer, 1954) in relation to the onset, evolution, and activity of the disease (Bonomo, 1957). The most important pattern consists generally of a predomi...

Serum immunoglobulins and the risk of rheumatoid arthritis.

OBJECTIVE Rheumatoid arthritis (RA) is associated with several autoantibodies that can precede the clinical disease. The immunoglobulin concentrations in serum samples before illness were studied to learn more about the immunological process before RA. METHODS A case-control study was nested within a Finnish cohort of 19,072 adults who had neither arthritis nor a history of it at the baseline...

Anticardiolipin Antibodies in Juvenile Rheumatoid Arthritis and Systemic Lupus Erythematosus

Background: Antiphospholipid antibody syndrome (APS) can either occur as a primary syndrome or associated with other autoimmune diseases such as systemic lupus erythematosus (SLE). Anticardiolipin antibody (aCL) of IgG and/or IgM isotype in blood, measured by a standardized ELISA is the most acceptable laboratory criteria. APS IgG isotype, particularly IgG2 subclass is more strongly associated ...